The Effect of Eight Weeks of Low Intensity Aerobic Exercise on Serum Levels of VIP and ET-1 Hormones in the Non-Athlete Healthy Elderly Women and Patients with Coronary Artery Disease

Report of Health Care

مقاله 4، دوره 5، شماره 3، مهر 2019، صفحه 24-32   

نوع مقاله: Original Article

نویسندگان

Maryam Amirazodi¹؛ Amin Mehrabi²؛ Zeinab Kordestani³؛ Hadi Habibi⁴؛ Kouros Divsalar^{* 5}

¹Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

²Department of Exercise Physiology, Kish International Campus, University of Tehran, Kish, Iran

³Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran

⁴Department of Physical Education, University of Kharazmi, Tehran, Iran

⁵Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran. Swimming Board of Kerman Province, Iran Swimming Federation

تاریخ دریافت: 16 دی 1397،  تاریخ پذیرش: 16 تیر 1398 

چکیده

Introduction: The objective of the present study is to evaluate the effect of eight weeks of low intensity aerobic exercise on serum levels of vasoactive intestinal peptide (VIP) and Endothelin-1 (ET-1) hormones in the Non-Athlete Healthy Elderly Women and Patients with Coronary Artery Disease. Methods: 15 females with the coronary artery disease and 15 healthy females were randomly selected for experimental and control groups, respectively. For eight weeks, the participants participated in aerobic exercises three times a week at a constant intensity of 100 ± 10 heart beats per minute. To evaluate VIP and ET-1 hormonal changes, blood samples of all participants were taken 3 times (before, immediately after the last session and 24 hours after last session). Repeated Measures ANOVA test was used to evaluate changes in the VIP, ET-1, and blood pressure. Pearson correlation coefficient Test was used to compare two variables in the control and experimental group. Results: Data analysis did not show any significant difference in the levels of VIP and ET-1 serum before, immediately after and 24 hours after the 24th session in the control group (P=0.52 and P=0.15, respectively) and the patients group (P=0.46 and P=0.22, respectively). Conclusion: Low intensity aerobics exercise will not change the serum VIP and ET-1 levels in the elderly women. Even though this result showed the same amount of VIP and ET-1 level in the healthy women and the patients with coronary artery diseases, the conclusion is that cardiac patients can undergo the progressive exercise programs and withstand higher intensity of exercise.

کلیدواژه‌ها

Exercise؛ Endothelin-1؛ Vasodilator Intestinal Peptide؛ Coronary Artery Disease

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