The Ability of NCP@POCl2-x Core-Shell Magnetic Nano-Catalyst for Simultaneous Conversion of Epoxides into Cyanohydrin and α,β-Unsaturated Carboxylic Acid

Journal of Optoelectronical Nanostructures

مقاله 4، دوره 9، شماره 2 - شماره پیاپی 28، مرداد 2024، صفحه 64-78   

نوع مقاله: Articles

شناسه دیجیتال (DOI): 10.30495/jopn.2024.32960.1309

نویسنده

Farzaneh Ebrahimzadeh^*

Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran

تاریخ دریافت: 24 دی 1402،  تاریخ بازنگری: 14 خرداد 1403،  تاریخ پذیرش: 15 خرداد 1403 

چکیده

Abstract:
This paper presents a new environmental, and remarkably efficient heterogeneous magnetic nanocomposite, NCP@POCl_2-x (Fe₃O₄@SiO₂@CS@POCl_2-x), designed for the regioselective production of cyanide compounds from epoxides using NaCN, subsequently facilitating the synthesis of α,β-unsaturated carboxylic acids. The reactions were conducted under mild conditions, demonstrating the catalyst's remarkable performance with high yields. The presence of POCl_2-x and the influence of water and heat facilitated the transformation of epoxides into cyanohydrin and α,β-unsaturated carboxylic acids. Remarkably, the reactions demonstrate excellent regioselectivity, producing clean and quantitative products. NCP@POCl_2-x is a heterogeneous magnetic nanocatalyst with a strong magnetic core of Fe₃O₄ surrounded by chitosan as a green layer and functionalized by the POCl_2-x group. This catalyst can be easily separated using external magnetic force. The combination of heterogeneity, magnetic properties, easy recovery, and exceptional performance establishes NCP@POCl_2-x as a valuable tool for efficient and selective transformations of epoxides. 

کلیدواژه‌ها

α؛ β-Unsaturated Carboxylic Acid؛ Cyanohydrin؛ Epoxide؛ Magnetic Chitosan؛ Nanocatalyst

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